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MCT2E (Monocarboxylate Transporter 2E) and HCN-R200 (a specific type of hyperpolarization-activated cyclic nucleotide-gated channel) serve different functions in cellular physiology. MCT2E is primarily involved in the transport of monocarboxylates like lactate and pyruvate across cell membranes, playing a crucial role in metabolic processes. In contrast, HCN-R200 is a channel that facilitates ion flow, particularly sodium and potassium, contributing to the regulation of neuronal excitability and heart rhythm. Thus, their primary difference lies in their roles: one is a transporter involved in metabolism, while the other is an ion channel influencing electrical signaling.
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