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Yes, polar compounds typically travel farther in Thin Layer Chromatography (TLC) compared to non-polar compounds due to their stronger interactions with the polar stationary phase.

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6mo ago

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Why does fluorenone travel in methylene chloride?

Presumably you are talking about in a chromatography column with alumina in it. The fluorenone is polar and subsequently creates a bond with the polar alumina. However, as Chlorine is more electronegative then the oxygens on alumina, the fluorenone wants to hang out and be friends with the methylene chloride even more than alumina, so the fluorenone and the methylene chloride hold hands and take a romantic walk down the column into your solution.


Why do some compounds travel further on TLC plates than others?

Compounds with lower polarity tend to travel further on TLC plates because they interact less with the stationary phase and are more soluble in the mobile phase. Compounds with higher polarity interact more with the stationary phase, thus travel a shorter distance.


Why polar compounds have less Rf value?

Polar compounds have less Rf (retardation factor) values in chromatography because they interact more strongly with the polar stationary phase, leading to slower movement through the mobile phase. This stronger interaction results in a higher retention time, causing the compound to travel a shorter distance compared to non-polar compounds. As a result, polar compounds have lower Rf values as they exhibit less movement relative to the non-polar compounds in the chromatographic system.


How does an HPLC work to separate and analyze compounds in a sample?

High Performance Liquid Chromatography (HPLC) works by using a liquid solvent to separate compounds in a sample based on their interactions with a stationary phase. The sample is injected into a column where the compounds travel at different speeds, allowing for separation. Detection methods like UV spectroscopy or mass spectrometry are then used to analyze and quantify the separated compounds.


How far do polar molecules travel in thin-layer chromatography (TLC)?

Polar molecules travel a shorter distance in thin-layer chromatography (TLC) compared to non-polar molecules.

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Do Tampa bay Buccaneers travel farther when the play the Rams St. Louis or the Cowboys in dallas?

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Do the Tampa Bay Buccaneers travel farther when they play the Rams in St. Louis or the Dallas cowboys?

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Do the Tampa bay Buccaneers travel farther when the play the st Louis rams or the cowboys in dallas?

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