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If it is fresh blood, strip the sheets off the bed immediately, put a cake of Irish Spring or Ivory Soap in a scrubby net, scrub the spot with the soap and net vigorously until the stain has diminished, then put the sheet in the washing machine and wash it as you would normally. (You can wash it with other things such as shirts and pants, but if the blood didn't come out well with the scrubbing treatment, you might want to make sure they are old shirts that you don't really care about. Or you could just make it a 'small' load and put in just the sheets)

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