How do you demetallate a hemeprotein?

Answer 1

Using nuclear magnetic resonance which targets the frequency of iron

Answer 2

One way to demetallate a hemeprotein is to use a chelating agent, such as ethylenediaminetetraacetic acid (EDTA), which binds to the metal ion in the heme group and removes it from the protein. Another method is to use reducing agents, such as sodium dithionite, which can break the bond between the metal ion and the protein.