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Well, unlike competitive inhibitors the non-competitive inhibitors will not compete the active site of the enzyme with substrate . Instead, it will combine with the enzyme somewhere except the ative site and alter the whole shape of the enzymes therefore the active site of substrate and enzyme are not the same and therefore no enzyme-substrate complex can be formed and the enzymatic effect can't be restored becausr the enzymes are now denatured
Wiki User
∙ 9y ago
Wiki User
∙ 14y agoA "non-competitive activator" doesn't exist; however, there is a non-competitive inhibitor. An inhibitor would inhibit a process, holding it back. A non-competitive inhibitor would decrease enzyme activity.
Wiki User
∙ 11y agoit unravels the enzyme causing it to denaturate
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When the noncompetitive inhibitor is bonded to the enzyme?
The shape of the active site is distorted.
What is an enzyme that is blocked?
Inhibited. Competitive, noncompetitive, allosterically and so on.
What is the effect of hydrochloric acid on the enzyme activity?
Denature enzyme activity
Difference between activator and prosthetic groups?
Prosthetic groups can be as simple as a single metal ion bound into the enzyme's structure, or may be a more complicated organic molecule (which might also contain a metal ion). it is permanently bonded to enzyme. Activator is only metal ion that is detachable. source:chemguide.co.uk Stuffidious.com
How does the presence of HCl affect activity of peroxidase?
The optimum pH for activity of Peroxidase is 5-7 that is about neutral. The Hydrochloric acid reduces the pH and thus inactivates the enzyme with reducing pH.
What modify's the rate of enzyme activity.?
Several factors affect the rate at which enzymatic reactions proceed - temperature, pH, enzyme concentration, substrate concentration, and the presence of any inhibitors or activator
When the noncompetitive inhibitor is bonded to the enzyme?
The shape of the active site is distorted.
What would be the likely outcome if you increased the concentration of substrate for an enzyme in the presence of a noncompetitive inhibitor?
No change in enzyme activity would be observed.
A noncompetitive inhibitor has a structure that?
A noncompetitive inhibitor has a structure that does not resemble the substrate structure. A compound that binds to the surface of an enzyme, and changes its shape so that a substrate cannot enter the active site is called a noncompetitive inhibitor.
Does a non-competitive inhibitor enhance the activity of an enzyme?
No. Remember what "inhibit" means: to hold back; restrain. Both non-competitive and competitive inhibitors affect enzymes by preventing the substrate from binding, though they differ in their methods. The opposite of an inhibitor is called an activator. So when you see the word "inhibitor," you know the functionality of the enzyme will decrease, and when you see the word "activator," you know the functionality of the enzyme will increase. The adjective before "inhibitor" or "activator" will ultimately tell you how the enzyme is inhibited or activated.
How do competitive and noncompetitive inhibitions differ?
A competitive inhibitor often binds to an enzyme's active site. Noncompetitive inhibitors usually bind to a different site on the enzyme.
Competitive and noncompetitive enzyme inhibitors differ with respect to?
the precise location on the enzyme to which they bind
What is an enzyme that is blocked?
Inhibited. Competitive, noncompetitive, allosterically and so on.
What environment factors can affect the activity of an enzyme?
temperature
What can effect how the enzyme and substrate come together?
Shape of substrate, shape of the enzyme, Competitive, noncompetitive and allosteric inhibitors.
What affect does too much substrate have on the rate of an enzyme reaction?
The enzyme becomes saturated by the substrate and enzyme activity plateaus.
Does freezing a enzyme affect it?
When an enzyme is frozen, it only slows down activity. Unlike boiling an enzyme, it does not stop it from working.
