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How has the level of hormones in the combined pill changed since it was first developed?
Wiki User
∙ 6y ago
The first version was made in the 1950's which contained a high level of oestrogen and progesterone. But soon, there were side effects of oestrogen like blood clots. Therefore, the pill right now has a lower dose of oestrogen so that means lower side effects.
Wiki User
∙ 6y ago
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