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Q: Is difluoromethane electron withdrawing
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Related questions

Is pyridyl group electron donating or electron withdrawing?

it's electron-withdrawing group.


List of electron withdrawing group?

the halogens are electron withdrawing groups. e.g. F, Cl, etc


Is alkyle group is electron withdrawing?

no!


Which is more acidic aniline or ammonia?

aniline is more acidic because in aniline a electron withdrawing benzene is connected.electron withdrawing capacity of benzene is due to its delocalizing pi electrons cloud.due the action of benzene the presence of unshared pair of electron over nitrogen is somehow decreases.which increases its acidic nature. But in case of ammonia there is no electron withdrawing group.so its unshared pair of electron remains undistrubed,which decreases its acidity and increases its basisity


How picric acid is strong acid?

for three electron withdrawing nitro groups, picric acid is highly acidic


Is trifluoroacetic acid stronger than acetic acid?

yes. due to the presence of electron withdrawing flourine atoms


What makes penicillin V more stable than penicillin G?

because electron-withdrawing group on side chain


Is R-410A halogenated?

Yes, beecause contain fluorine as difluoromethane and pentafluoroethane.


How can the hydrolysis rate of prodrugs be accelerated?

If the base hydrolysis mechanism is important, an electron withdrawing group can be attached to the prodrug. If the acid hydrolysis mechanism is important, an electron donating group can be attacked to the prodrug.


What substituents have a positive Hammet substituent constant?

Substituents with a positive Hammet substituent constant are electron withdrawing. Examples include CF3.


Why does electron withdrawing groups increase acidity?

Assuming the groups are conjugated to the acid/base groups: An acid wants to lose a proton. When it loses a proton, you form an anion (or a neutral molecule, but when talking about electron donating/withdrawing groups, you assume there is a charge). The more stable the anion, the more easily the proton comes off, and the more acidic it is. A base is the opposite. A base gains a proton to become cationic. The more stable the cation, the more likely it is to pick up a proton, and the more basic it is. An electron withdrawing group can stabilize an anion (and thus make something more acidic) and an electron donating group can stabilze a cation (and make something more basic). The opposites also hold true: an electron donating group can destabilize an anion and make something less acidic, and vice versa for bases.


How can penicillin be structurally modified so that it is less sensitive to acid?

An electron withdrawing group can be added at position 6 of the bicyclic system. Its inductive effects can reduce nucleophilicity.