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3 Atoms:

H2 is 2 atoms, since the subscript is a 2;

O is obviously singular.

2 + 1 = 3.

Coefficients, however, are different. You cannot change the subscript without changing the type of molecule (O is oxygen, which doesn't exist all by itself, O2 is in the air you breathe, and O3 is ozone) but coefficients can be changed because they only affect the amount of the molecules you have.

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