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Some cultures are live and/or involve active elements which, over time, can slightly or drastically (depending on the specimen collected and the amount of time) undergo changes due to chemical reactions, natural occurrences, and other variables. Furthermore, some specimens The Order of Draw method is used in order to test cultures in a manner that reduces the chance of contamination as it establishes practices that are based on knowledge of different cultures and their associated hazards, reactions, etc.

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