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What are the differences between HSQC and HMQC experiments in NMR spectroscopy?

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Sierra Flatley ∙

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∙ 6mo ago
Updated: 2/7/2025

In NMR spectroscopy, HSQC and HMQC experiments are both used to correlate signals from different nuclei in a molecule. The main difference between them is that HSQC correlates proton signals with carbon signals, while HMQC correlates proton signals with other heteronuclei signals, such as nitrogen or phosphorus.

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What are the differences between HMQC and HSQC experiments in NMR spectroscopy?

In NMR spectroscopy, HMQC and HSQC experiments are both used to correlate proton and carbon signals in molecules. The main difference between the two experiments lies in the type of nuclei they correlate. HMQC correlates protons with directly bonded carbons, while HSQC correlates protons with directly bonded heteronuclei, such as nitrogen or phosphorus.


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What are the differences between HMQC and HSQC experiments in NMR spectroscopy?

In NMR spectroscopy, HMQC and HSQC experiments are both used to correlate proton and carbon signals in molecules. The main difference between the two experiments lies in the type of nuclei they correlate. HMQC correlates protons with directly bonded carbons, while HSQC correlates protons with directly bonded heteronuclei, such as nitrogen or phosphorus.


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