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What are the potential applications of the mosher ester in organic chemistry?

Rahul Ledner ∙

Lvl 10

∙ 6mo ago

Updated: 2/7/2025

The mosher ester is commonly used in organic chemistry for determining the stereochemistry of chiral alcohols and carboxylic acids. It is particularly useful in analyzing the configuration of molecules and studying their reactions.

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∙ 6mo ago

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What are the key steps involved in conducting a Mosher ester analysis?

The key steps involved in conducting a Mosher ester analysis include: Preparing the sample by synthesizing the Mosher esters from the compound of interest. Analyzing the sample using NMR spectroscopy to determine the chemical shifts of the protons in the Mosher esters. Comparing the chemical shifts of the protons in the Mosher esters with a reference database to determine the absolute configuration of the original compound.

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