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The amide link is produced from the condensation reaction of an amino group and a carboxylic acid or acid chloride group. A small molecule, usually water, or hydrogen chloride, is eliminated.

The amino group and the carboxylic acid group can be on the same monomer, or the polymer can be constituted of two different bifunctional monomers, one with two amino groups, the other with two carboxylic acid or acid chloride groups.

Amino acids can be taken as examples of single monomer (if the difference between R groups is ignored) reacting with identical molecules to form a polyamide:

The reaction of two amino acids. Many of these reactions produce long chain proteins

Aramid (pictured below) is made from two different monomers which continuously alternate to form the polymer and is an aromatic polyamide:

The reaction of 1,4-phenyl-diamine (para-phenylenediamine) and terephthaloyl chloride to produce Aramid

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