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This test uses prokaryotes which means it isn't a perfect model for humans even after rat liver enzymes are added. Mutagens this test finds might also not be carcinogenic, meaning further tests are required. In addition not all carcinogens are mutagens (such as asbestos) meaning this test won't find them. Finally, some nitrate-containing substances can cause a false positive by production of nitric oxide. An example of this is nitroglycerin which is still widely used in treatment but gives a positive Ames result. Hope this is useful!

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Q: What are the limitations of the Ames Test?
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What is the purpose of the ames test?

The Ames test identifies chemical mutagens.


Can you reduce animal killing using AMES test?

not with ames but with animes


Are substances that test positive with the Ames test necessarily carciongenic in humans?

The substances that are test positive with Ames test may or may not be carcinogenic for humans. Similarly, some substances that cause cancer in laboratory animals do not give a positive result Ames test. It is not possible to decide the carcinogenicity of any substances only depending on the Ames test.


In what field of science would one carry out an Ames test?

Ames test would typically be carried out in the field of biology, more specifically toxicology. The Ames test involves testing genetics, which involves taking a sample and examining it closely in a laboratory.


What is the test used for detecting chemicals with carcinogenic potential?

The Ames Test


What are the limitations of benzidine test?

The benzidine test is a test for cyanide. The limitations of this test are that benzidine has been linked to bladder and pancreatic cancer.


Describe the control component in an Ames Test?

The Ames test is a quick method that uses bacteria to assay for cancer causing chemicals. A false positive is possible when a nitrogen based material is used.


Purpose of liver extract in the Ames test?

Ames test is used to test whether a certain substance is mutagenic. Liver extract is optionally added to simulate the effect of metabolism, as some compounds, like benzo[a]pyrene, are not mutagenic themselves but their metabolic products are.


Are there limitations to the oxidase test?

There are none.


When did Blanche Ames Ames die?

Blanche Ames Ames died in 1969.


When was Blanche Ames Ames born?

Blanche Ames Ames was born in 1878.


Can you be 17 and buy a pregnancy test?

Yeah you can, there is no age limitations.