During anaerobic conditions, pyruvate is converted to lactic acid or ethanol via fermentation pathways to regenerate NAD+ for glycolysis to continue. This process does not produce additional ATP and is less efficient than aerobic respiration.
When oxygen is available, pyruvate enters the mitochondria to undergo aerobic respiration. In the mitochondria, pyruvate is converted into acetyl-CoA in the presence of oxygen, leading to the production of ATP through the Krebs cycle and oxidative phosphorylation.
In the absence of oxygen, pyruvate is converted into lactate through a process called fermentation. This allows for the regeneration of NAD+ so that glycolysis can continue to produce ATP in the absence of oxygen.
If oxygen is available, the pyruvate produced during glycolysis enters the mitochondria and undergoes aerobic respiration. In the presence of oxygen, pyruvate is converted to acetyl CoA, which enters the citric acid cycle to generate more ATP through oxidative phosphorylation. This process enables the efficient extraction of energy from glucose molecules.
Glycolysis, in the presence of oxygen, is the first stage of cellular respiration where glucose is broken down into pyruvate. This process occurs in the cytoplasm of the cell and produces a small amount of ATP and NADH. The pyruvate then enters the citric acid cycle to further extract energy from it.
Pyruvate processing occurs in the mitochondria of eukaryotic cells. It is an important step in cellular respiration where pyruvate is converted to acetyl-CoA before entering the citric acid cycle to generate ATP.
they will enter the Krebs cycle
The lactate is taken to the liver and converted back to pyruvate.
When oxygen is available, pyruvate enters the mitochondria to undergo aerobic respiration. In the mitochondria, pyruvate is converted into acetyl-CoA in the presence of oxygen, leading to the production of ATP through the Krebs cycle and oxidative phosphorylation.
Molecular oxygen
lactate
In the absence of oxygen, pyruvate is converted into lactate through a process called fermentation. This allows for the regeneration of NAD+ so that glycolysis can continue to produce ATP in the absence of oxygen.
There are three carbon atoms and three oxygen atoms in each pyruvate molecule.
acetyl CoA
During alcohol fermentation, pyruvate, produced from glycolysis, is converted into ethanol and carbon dioxide. This process occurs in anaerobic conditions, where the pyruvate is first decarboxylated to form acetaldehyde, which is then reduced to ethanol by the enzyme alcohol dehydrogenase. This conversion regenerates NAD+, allowing glycolysis to continue and produce ATP in the absence of oxygen.
Acetyl CoA forms.
Pyruvate is the result of glycolysis, the degradation of a molecule of glucose. In aerobic conditions (with O2 present), pyruvate is oxidized to H2O and CO2 via the citric acid cycle and oxidative phosphorylation to produce energy (ATP). In anaerobic conditions (low levels of O2), pyruvate metabolism goes in two directions: in yeasts, an alcoholic fermentation takes place (with the production of two CO2 molecules + two molecules of ethanol); while in muscle, homolactic fermentation occurs (with the result of 2 molecules of lactate).
glucose is changed into pyruvate