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The Perkin condensation is a reaction where an aromatic aldehyde reacts with an anhydride in the presence of an acid catalyst to form a β-keto ester. This reaction is named after English chemist William Henry Perkin.

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1y ago

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Why perkin reaction is not possible for aliphatic aldehyde?

The Perkin reaction typically involves the condensation of aromatic aldehydes with an acid anhydride in the presence of a base to form an α,β-unsaturated carboxylic acid. Aliphatic aldehydes lack the necessary stabilization of the intermediate enolate ion due to the absence of conjugation with an aromatic ring, making the Perkin reaction unfavorable for aliphatic aldehydes.


What is the mechanism for perkin reaction?

Start with the aromatic aldehyde and acid anhydride. Salt of an Carboxylic acid is used to abstract a proton from the alpha carbon of acid anhydride. The carbanion generated would attack the electrophillic centre of aldehyde. This centre is carbonyl carbon. There after an stablised anion is formed. Further hydrolysis gives the required Cinnamic acid.


When was Perkin Medal created?

Perkin Medal was created in 1906.


When did Graham Perkin die?

Graham Perkin died in 1975.


When was Graham Perkin born?

Graham Perkin was born in 1929.


When did Harold Perkin die?

Harold Perkin died in 2004.


When was Harold Perkin born?

Harold Perkin was born in 1926.


When was Perkin Warbeck born?

Perkin Warbeck was born in 1474.


What has the author George Perkin written?

George Perkin has written: 'Pedestrian progress'


When was The Fortunes of Perkin Warbeck created?

The Fortunes of Perkin Warbeck was created in 1830.


When did Richard Scott Perkin die?

Richard Scott Perkin died in 1969.


When was Richard Scott Perkin born?

Richard Scott Perkin was born in 1906.