0
What else can I help you with?
What are the disadvantages a prodrug?
Some disadvantages of prodrugs include potential variability in conversion to the active drug due to individual differences in metabolism, the risk of inactive metabolites causing toxicity, and the need for additional steps in drug processing which can complicate drug development and regulation.
What is preformulation studies?
Preformulation studies involve the physicochemical characterization of a drug substance in preparation for formulation development. These studies help in understanding the drug's solubility, stability, compatibility with excipients, and other factors that can impact its formulation. Overall, preformulation studies provide critical information that guides the formulation process for drug development.
What is 'first pass mechanism' in pharmacology?
In pharmacology, the first-pass mechanism refers to the initial metabolism of a drug in the liver before it reaches systemic circulation. This process can significantly reduce the bioavailability of the drug, meaning less of the drug reaches its target site in the body. It is an important consideration when determining drug dosage and route of administration.
How does drug absorption through the skin occur and what factors influence this process?
Drug absorption through the skin, also known as transdermal absorption, occurs when a drug penetrates the skin layers and enters the bloodstream. Factors that influence this process include the drug's molecular size, lipophilicity (ability to dissolve in fats), skin thickness, blood flow to the skin, and the presence of enhancers or barriers on the skin.
Difference between entrapment efficiency and drug loading efficiency of microspheres?
1. Entrapment efficiency is the ratio of wt. of drug entrapped into a carrier system to the total drug added. 2. Drug loading is the ratio of drug to the weight of total carrier system (all excepients taken together).
When was TGen Drug Development created?
TGen Drug Development was created in 2003.
What is TGen Drug Development's population?
The population of TGen Drug Development is 24.
What are the disadvantages a prodrug?
Some disadvantages of prodrugs include potential variability in conversion to the active drug due to individual differences in metabolism, the risk of inactive metabolites causing toxicity, and the need for additional steps in drug processing which can complicate drug development and regulation.
Steps in preparing drug for commercial market?
There are following steps are invoved in prepration of drug for commercial market;CultivationCollection.Harvesting.Adulteration.Drying.Garbling.Packing and labeling.Storage.Preservation.
What is preformulation studies?
Preformulation studies involve the physicochemical characterization of a drug substance in preparation for formulation development. These studies help in understanding the drug's solubility, stability, compatibility with excipients, and other factors that can impact its formulation. Overall, preformulation studies provide critical information that guides the formulation process for drug development.
What are two reasons for the development of drug tolerance?
Repeated exposure to a stimulus could increase the development of drug tolerance.
Which steps must take place before the pharmaceutical company can test the drug on human volunteers?
Must be tested by animals first.
What are the four steps that lead to drug dependence?
The four steps that lead to drug dependence are experimentation, regular use, risky use, and addiction. Experimentation involves trying the drug for the first time. Regular use occurs when the drug is used consistently. Risky use involves using the drug in dangerous situations or in larger amounts. Finally, addiction is characterized by a physical and psychological dependence on the drug.
What are the barriers to development?
Some of the barriers to development include vices such as crime and drug abuse. When the greater population is struggling with drug addiction, they do not contribute much to economic development.
Who pays for drug development?
consumers
What is the Process of transporting a drug from administration site to its site of action?
The process of transporting a drug from its administration site to its site of action involves several key steps: absorption, distribution, metabolism, and excretion. After administration, the drug is absorbed into the bloodstream, where it is then distributed throughout the body via the circulatory system. Once at the target site, the drug may undergo metabolic processes that can activate or deactivate its effects. Finally, the drug and its metabolites are eliminated from the body, primarily through the kidneys or liver.
What is the mission of First Steps?
First Steps is a forum which is set up to provide support, to educate and to provide hope to those suffering from drug addiction and those currently in treatment. More information is on the West End Mt Carmel Community Outreach Service.
