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What is the maximum number of water molecules that in theory one asparagine molecule at pH 7 could hydrogen bond with?
Wiki User
∙ 13y ago
13/Thirteen
A Hydrogen bond forms between a hydrogen atom bonded to a strongly electronegative atom of one molecule and a strongly electronegative atom of another molecule.
A strongly electronegative atom such as nitrogen or oxygen may have a slightly negative charge, and then hydrogen atom or atoms bonded to it will have a slightly positive charge. (The difference in the electronegativity values between hydrogen and nitrogen is 0.84; therefore the N-H bonds are polar)
Nitrogen:
~NH3+: The nitrogen atom of the NH3+ group does not have any unshared electrons, and does not take part in hydrogen bonding.
~NH2: The nitrogen atom has one unshared pair of electrons and can from one hydrogen bond.
Oxygen:
~The oxygen atoms of the C=O groups each have two unshared pairs of electron and can form two hydrogen bonds with hydrogen atoms, for a total of four hydrogen bonds.
~The negatively charged oxygen atom of the carboxylate group (C))-) has three unshared pairs of electrons and can potentially form three hydrogen bonds.
Hydrogen: Each hydrogen atom bonded to nitrogen or oxygen can form a hydrogen bond with an oxygen atom in water, for a total of five hydrogen bonds.
Asparagine can theoretically form hydrogen bonds with 13 water molecules. However, the size and shape of the molecule, in addition to other factors, limits the number of hydrogen bonds formed.
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∙ 13y ago
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