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[HgI4]-(aq) reacts with the lone pairs of nitrogen that are present, then the typical off-white precipitate falls out. A uncharged Mercury salt is thus obtained. In some alkaloids there isn't a reaction with Mayer's reagent because it lacks lone pairs (example berberine) and it reacts also with alkaline peptides. This mechanism is actually similar then Dragendorff's reagent.

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9y ago
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9y ago

Mayer reagent (for narcotic alkaloids) "... can be created by dissolving 1.358

grams of HgCl2 in 60 milliliters of water, and pouring that solution into a solution

of 5 ...

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Q: What is the mechanism of the reaction between mayer's reagent and an alkaloid?
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