Doxofylline Pka value is about 9.8.
pKa = 15
It is around pKa=13
The pka of a protonated ether (the conjugate acid) is about -3.5
7.6
pKa = 6.36 of carbonic acid to HCO3-
pKa = 15
It is around pKa=13
Drugs that may interact with Doxofylline are Allopurinol, Cimetidine, Clindamycin, Eythromycin, Lincomycin, Propranolol, and Ranitidine. There may be other drugs that react with Doxofylline, so always inform your doctor of any drugs that you are taking. Doxofylline is used to treat asthma and COPD.
By following + or - 2 pH to the pKa value
The pka of a protonated ether (the conjugate acid) is about -3.5
The conjugate acid is Hydrogen (H2), the pKa of which is 35.
3.3
7.6
if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.
pKa = 6.36 of carbonic acid to HCO3-
actual pka of betaxolol is 9.4 but observed is 9.38
The pKa of sulfonic acid is < 0