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What is the polarity of phenacetin?

Updated: 8/10/2023
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12y ago

Best Answer

It is certainly a polar molecule, although the exact value of it dipole moment I don't know.

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16y ago
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9y ago

Yes, paracetamol is polar. It is polar due to the hydroxyl functional group OH. The OH group is at one end so that it is able to form a hydrogen bond.

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12y ago

non polar

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Q: What is the polarity of phenacetin?
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What are the disadvantages of phenacetin mining?

Phenacetin is not mined, it is a synthetic pain-relieving and fever-reducing drug.


Why is acetaminophen soluble in 5 percent sodium hydroxide but phenacetin is not?

Acetminophen is solube in 5% NaOH, and phenacetin is not because acetminophen is a stronger acid than water, and phenacetin is not appreciably acidic.


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Originally, Saridon contained phenacetin. However, when it was discovered that phenacetin was carcinogenic and had a link to analgesic-induced nephropathy, Saridon was reformulated without this ingredient.


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Acetaminophen's solubility: 0.1-0.5 g/100 mL at 22 C (Very slightly soluble) Phenacetin's solubility: 0.076 g/100 mL Acetaminophen contains Amide & Alcohol groups, thus makes it really polar whereas Phenacetin contains Ether & Amine that are less polar.


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-- negative polarity -- positive polarity


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