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drotaverine is soluble in methanol, tetra hydro furan, dichloro methane and ammonium acetate buffer (0.01 M, pH=5)

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What is the BCS class of drotaverine hydrochloride?

Drotaverine hydrochloride is classified under the Biopharmaceutical Classification System (BCS) as a Class II drug. This indicates that it has high permeability but low solubility. As a result, its absorption can be influenced by the solubility characteristics, making formulation and administration considerations important for effective therapeutic use.


What is the pKa of drotaverine?

The pKa of drotaverine is around 8.67.


Difference in the solubality of ciprofloxacin in water and 0.1N HCl solution i-e. I mean to ask that either in water or 0.1 N HCl solution the ciprofloxacin is more soluble?

Ciprofloxacin is more soluble in 0.1 N HCl solution compared to water. The solubility of ciprofloxacin increases in acidic solutions like HCl due to its acidic nature, which helps to increase its solubility in the 0.1 N HCl solution.


Pantoprazole drug profile including its solubility?

solubility of pentoprazole drug


Will calcium stearate dissolve in Hcl?

No, calcium stearate is insoluble in hydrochloric acid (HCl). It will not dissolve in HCl due to its low solubility in acidic solutions.


What are the Administration guidelines to drotaverine injection in chlidren?

Generally pediatric administration of drotaverine is not recommended by most of pharma companies. LUCKY...


Solubility of Ambroxol Hcl in pH 6.8?

The solubility of Ambroxol HCl can vary depending on the specific conditions. Generally, Ambroxol HCl is more soluble in acidic pH than neutral pH. At pH 6.8, the solubility of Ambroxol HCl may be lower compared to acidic pH. Further experimental testing may be needed to determine the specific solubility at pH 6.8.


Is the solubility of HCl in water a physical phenomenon or a chemical reaction?

Dissolving HCl (or any other dissolvable compound, eg. sugar, salt) in water is physical.


Why does a precipitate form when HCl is added to a saturated solution of NaCl?

The constant solubility product is modified.


What is the effect of a common ion on dissolution rate?

A common ion will reduce the solubility of an electrolyte with an identical ion. The common ion will hence also reduce the dissolution rate of the electrolyte. For example, the solubility of a HCl salt of a weak organic base may be reduced in a HCl solution.


Why is Cl2 less soluble than HCl?

Because, HCl (Hydrochloric acid) Is a VERY strong acid. It is soluble in very few things. Most things are soluble IN HCl. Not the other way around. The more acidic it its, the less soluble it is.


When HCl gas is added to saturated solution of NaCl then what is the effect in the solubility of NaCl?

The common ion is chloride (Cl-).