Cl- is the superior leaving group because halides form the most stable anions. The stability of an anion reflects its ability to bear a negative charge and accept electrons, which is the function of a good leaving group.
Iodide is a better leaving group than chloride so iodomethane would react faster.
Bromine is bulky when compared to chlorine and hence a better leaving group.
Based on pKa, hydride would be better (~35 vs. ~45), but there are very few reactions where either would act as a leaving group.
Cyanide and nitriles can be grouped together. A nitrile is an organic compound that contains a cyanide (CN) group. However, other substances often called cyanide are not nitriles, including hydrogen cyanide, sodium cyanide, and potassium cyanide.
Id you are talking about acid derivative, mix the chloride with ammonia.
Iodide is a better leaving group than chloride so iodomethane would react faster.
Bromine is bulky when compared to chlorine and hence a better leaving group.
the aminoacid reacts as a standard nucleophile using nitrogen's free electron pair; the chloride is a better leaving group because of its lower basicity.
Based on pKa, hydride would be better (~35 vs. ~45), but there are very few reactions where either would act as a leaving group.
Nitrogen is a good leaving group. therefore,the gas is expelled when the compound is heated. no formation of sodium cyanide.
Cyanide and nitriles can be grouped together. A nitrile is an organic compound that contains a cyanide (CN) group. However, other substances often called cyanide are not nitriles, including hydrogen cyanide, sodium cyanide, and potassium cyanide.
Chloride Group was created in 1891.
emigration
emigration
Probably not. Cl- is a good nucleophile, but you have to first turn the OH group in 1-butanol into a good leaving group. The easiest way probably is to first react 1-butanol with tosyl chloride to form a tosylate (-OTs) group, which is an excellent leaving group, followed by addition of NaCl.
Although cyano isn't a very good leaving group (it IS a fantastic nucleophile, however), it is still better than an alcohol. The only way you can make an alcohol a good leaving group is to activate it somehow. Methods range from simple protonation (making [H-OH]+ - water) in an acidic environment, to tosyl-/mesylation to make OTs/OMs, to activation with a phosphorous reagent, etc.
It is- The principal process used to manufacture cyanides in which gaseous hydrogen cyanide is produced from methane and ammonia in the presence of oxygen and a platinem catalist. 2 CH4 + 2 NH3 + 3 O2 → 2 HCN + 6 H2O Gaseous hydrogen cyanide may be dissolved in aqueous sodium hydroxide solution to produce sodium hydroxide.