DNA is a linear polymer of nucleotides whose phosphates bridge the 3' and 5' positions of succesive 2-deoxy-D-ribose residues, and nitrogenous bases such as purines and pyrimidines. In detail, DNA is a) a helical molecule, and b) its planar aromatic bases form a stack of parallel rings that is parallel to the fiber axis.
There are several configurations of the DNA molecule. The A, B, and C forms of DNA are right-handed, double-stranded helices which, in fibrous form, are stable at intermediate, high, and low relative humidities, respectively, and have 11, 10, and 9.3 base pairs per turn of double helix. The left-handed helix of B-DNA structure is refered as Z-DNA (it contains 12 bases pairs per turn of double helix, and has only a single groove. B-DNA (the so-called Watson-Crick structure) is regarded as the native form because its X-ray pattern resembles that of the DNA in intact sperm heads, and is a double helix with around 20 angstroms diameter. The planes of the bases are nearly perpendicular to the helix axis and conserve the so-called "complementary base pairing" (that is, adenine base always is in front of a guanine base, as well as thymine is always in front of a cytosine.
The "ideal" B-DNA helix has 10 base pairs (bp ) per turn (a helical twist of 36o per bp) and, the aromatic bases have van der Waals thicknesses of 3.4 angstroms and are partially stacked on each other (known as base stacking). Finally, the helix has a pitch (rise per turn) of 34 angstroms.
The structure of DNA was described by James Watson and Francis Crick in 1953.
double helix composed of two strands that are twisted together. The strands are made up of nucleotides which consist of a sugar, phosphate group, and a nitrogenous base. This structure allows DNA to store and transmit genetic information.
A bond in DNA helps hold the structure together by connecting the nucleotide bases in the double helix. These bonds are essential for maintaining the stability and integrity of the DNA molecule.
Watson and Crick deduced the double helix structure of DNA. They proposed this model in 1953, revolutionizing our understanding of genetics and molecular biology.
The numbering of adenine in DNA is important for identifying its position in the DNA molecule. This numbering system helps scientists understand the structure and function of DNA, as well as how adenine interacts with other molecules in the cell.
1950
they described the structure of DNA
1950
1950
The structure of DNA was described by James Watson and Francis Crick in 1953.
watson and crick
Watson and Crick
Double stranded, single stranded. DNA can be described as having a double helix structure.
unconventional
Sir James Watson and Sir Francis Crick first described the molecular structure of DNA correctly. They not only mentioned the fact that DNA is a helical structure, but also described how the constituting molecules are arranged in the helix. The base-pairing, sugar-phosphate backbone were first described by Watson and Crick.
DNA is described as a double helix because its structure resembles a twisted ladder, with two strands that are twisted around each other in a spiral shape. This shape allows DNA to store and transmit genetic information efficiently.
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