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A person inherits one set of HLA haplotypes from each parent. Therefore, a woman's sons share half of their HLA haplotypes with her, as they inherit one set from her and one set from their father.

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1y ago

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What are HLA haplotypes?

HLA haplotypes are specific combinations of alleles at the human leukocyte antigen (HLA) gene loci, which are crucial for the immune system's function in recognizing foreign molecules. Each individual inherits one haplotype from each parent, resulting in a unique pair that influences compatibility for organ transplants and susceptibility to certain diseases. These haplotypes play a significant role in autoimmune conditions and the body's response to infections. Understanding HLA haplotypes is essential in fields like transplantation medicine and immunology.


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