To set the jumpers on a Quantum Fireball EX 6.4AT (EX64A02G), first ensure the drive is powered off and disconnected from the system. Locate the jumper block on the back of the drive and refer to the label on the drive or the user manual for the specific configurations. Typically, you'll set the jumpers to configure the drive as Master, Slave, or Cable Select, depending on your setup. After setting the jumpers, reconnect the drive and power on the system.