NT-proBNP (N-terminal pro b-type Natriuretic Peptide) is a biomarker released by the heart in response to ventricular wall stress and increased pressure, commonly associated with heart failure. It is a prohormone that gets cleaved to produce the active hormone BNP, which helps regulate blood pressure and fluid balance. Elevated levels of NT-proBNP in the blood can indicate heart dysfunction, making it a valuable tool for diagnosing and managing heart failure. Clinicians often use NT-proBNP testing to assess the severity of heart failure and monitor treatment response.