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Preload refers to the total volume of blood in the ventricles at the end of diastole, just before the heart contracts. It is often described as the degree of stretch of the cardiac muscle fibers, which is influenced by venous return and the filling of the heart. Higher preload generally increases stroke volume due to the Frank-Starling mechanism, where increased stretch leads to a more forceful contraction.

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1mo ago

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Does diuretics decrease preload or afterload?

it decreases blood volume and preload


Does stroke volume start with increased or decreased preload?

Stroke volume typically increases in response to increased preload, which is the volume of blood filling the heart during diastole. This increased preload stretches the heart muscle, leading to a more forceful contraction and higher stroke volume.


What causes decreased preload?

Preload is caused by decreased blood volume in ventricles. Therefore, decreased preload directly caused by bleeding, polyuria, dehydration.


How does dehydration affect preload?

Severe dehydration will decrease preload because there won't be as much volume coming into the heart.


The preload acting on a ventricle is equivalent to that chamber's?

end-diastolic volume


How can stroke volume can be altered?

Stroke volume is determined by three factors, altering any of them can change the stroke volume. These factors are preload, afterload, and contractility. The relationship is: SV = P*C/A What this means is that preload and contractility are directly proportional to the stroke volume and afterload is inversely proportional to stroke volume. If you increase preload (within certain limits), stroke volume will increase according to the Starling curve. Increasing contractility (many things can increase this), makes the heart pump harder and increases stroke volume. Increasing afterload decreases stroke volume. All of these can be reversed (decreasing preload and contractility = decreased stroke volume, etc). Get a good physiology book and it will explain all of this very well.


In a healthy individual which of the following would be low Contractility Preload Stroke volume or Afterload.?

afterload


What is a determinate of left ventricular preload?

Blood volume and pulmonary vein pressures, along with venous tone and rate or return are the major determinants of LV preload (or, clinically speaking, LV end-diastolic pressure, or LVEDP).


Does preload influence cardiac contractility?

Preload does not directly influence cardiac contractility, as they are distinct concepts. Preload refers to the degree of stretch of the cardiac muscle fibers at the end of diastole, which affects the volume of blood in the ventricles. While increased preload can enhance the force of contraction through the Frank-Starling mechanism, contractility itself is primarily influenced by factors such as sympathetic nervous system stimulation and circulating hormones. Thus, while preload can affect the overall cardiac output, it does so indirectly through its interaction with contractility.


Why do you need preload?

Preload is essential because it refers to the initial stretching of the heart muscle fibers before contraction, which directly influences cardiac output. Adequate preload ensures that the heart fills sufficiently with blood, optimizing the stroke volume and overall efficiency of the circulatory system. Insufficient preload can lead to reduced cardiac performance and inadequate tissue oxygenation, potentially resulting in heart failure or other cardiovascular issues. Thus, maintaining proper preload is vital for effective heart function and overall health.


How do you use preload in a sentence?

John is about to preload his truck with logs.


Why does nitrate drug decrease preload of heart?

Nitrate drugs decrease preload by dilating venous blood vessels, which reduces the volume of blood returning to the heart. This venodilation lowers the pressure and volume in the venous system, leading to decreased left ventricular filling. As a result, the heart experiences less stretch and workload during diastole, ultimately reducing the overall preload. This effect helps alleviate symptoms in conditions like heart failure and angina by decreasing cardiac demand.