express Sata basically you can make your internal hard drive external using your esata port the cables are basically the same so all you need is an enclosure that has an esata port, esata is for fast data transfer your can reach speeds over 90mbp/s transferring data.
Short answer: No. They are different and not compatible. Long answer: If the USB 2.0 device happens to be a hard drive that also has an esata port, then you could use the esata port instead.
SATA and eSATA are electonically the same, but the construction of the cables and the terminals is different. The major difference between the two is that SATA is designed for use inside a computer system while eSATA is for use externally.
MacBook Pro does not come with eSATA support. If you have MacBook Pro with ExpressCard support, you can get adapter which would allow you to use eSATA. Note: Latest MacBook Pro laptops do not come even with ExpressCard support. Firewire is the fastest available option right now (2010).
eSATA is the fastest of the three.
Look for the eSATA logo next to it. The eSATA logo looks exactly the same as the SATA logo, except that it has the lower case "e" before it.
eSATA is up to six times faster than USB or FireWire
An Esata port is a port you connect a ESata-compatible storage device (HDD/SSD) to. ESata stands for "External Serial ATA", and as opposed to normal SATA, this port can be found on the outside of the computer so you can easily connect Hard drives to your system. The 2 connectors can't be exchanged.
The companies found which product computers with an esata port are as follows: Hewlett Packard, Toshiba and LG. Esata ports could also be purchased as an external hard drive.
USB
Off the shelf you can purchase up to a 4 SATA to eSATA adapter, but you will need to contact suppliers directly through an internet search to see if they will custom build you a 5 SATA to eSATA adapter.
eSATA is faster than FireWire and firewire is faster than USB.
eSATA-600 at 6.0 Gbps while FireWire runs at 1.2 Gbps.