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Ultra-low Bleed Phenyl Phase with Enhanced Phenyl Selectivity
Phenyl-based reversed-phases were one of the first alternatives to C18 selectivity. Our Ascentis Phenyl has been improved to offer exceptional phase stability and enhanced phenyl retention. Ascentis Phenyl offers versatility by also operating in the HILIC mode.
Features
- Low-bleed for MS or UV gradient applications due to the use of trifunctional bonding reagent
- Outstanding phenyl selectivity due to high phase loading and short butyl spacer
- 100% aqueous-compatible for highly-polar compounds
Structure of Ascentis Phenyl
PropertiesUSP Code:L11Bonded Phase Description:Phenyl ring with short
butyl spacerEndcapped:YesParticle composition:Type B silica gelParticle Purity:<5 ppm metalsParticle Shape:SphericalParticle Size:3, 5 and 10 µmPore Size:100 ÅSurface Area:450 m2/gCarbon Load:19.5 %pH Range (recommended):2 to 8Extended pH range*:1.5 to 10
Key Applications
Small, water soluble molecules and peptides, π-acceptors, nitroaromatics, polar compounds, dipoles, heterocyclics, HILIC mode
Ordering Information for Ascentis Phenyl HPLC columns
Use
Phenyl phases are π-basic (electron donating) and are similar in overall retention to alkyl and EPG phases for easy column screening. The alternate selectivity of phenyl phases is often explained by the π-π interactions available through the phenyl ring. Compounds that appear to exhibit differential selectivity on the phenyl phase include:
- hydrophobic bases (TCAs, tetracyclines)
- moderate bases (anesthetics and narcotic analgesics)
- benzodiazepines
- some acidic compounds such as ACE inhibitors and quinoline antibiotics
- nucleosides (e.g. cytidine)
- nitro, azide and sulfonyl compounds
Notes
- Methanol can be a more selective mobile phase component than acetonitrile.
- Activate HILIC mode by using highly-organic (>90%) mobile phases.
What else can I help you with?
What is the use of phenyl?
what is the use of phenyl ?
What are the uses of phenyl?
The phenyl is used in the hair care formulations and cosmetics.
Is phenyl a functional group?
Yes, phenyl is a functional group.
What is phenyl magnesium bromide?
it has phenyl group to which Mgbr attached at first position
How to make phenyl?
"Phenyl" is only part of a name, you'll need to be more specific.
How do you make phenyl?
WE HAVE WHITE PHENYL SOLUTION FROM WHICH YOU CAN MAKE UPTO 50 LITERS OF WHITE PHENYLE. ONLY YOU HAVE TO ADD WATER TO THE SOLUTION SLOWLY.CONTACT US AT 9414033040, 9314813795 , aditya.rawat@gmail.comHINDAUN CITY, RAJASTHAN, INDIA
What is the common name for 3-phenyl-butanoic acid?
Its common name is B- phenyl butyric acid (B=Beta)
What is the name of the subtituent C6H5 in a benzene ring called?
The substituent C6H5 in a benzene ring is called a "phenyl" group.
What is the Prepration of phenyl benzoate from phenol?
To prepare phenyl benzoate from phenol, first convert phenol to phenyl benzoate by reacting it with benzoic acid and a catalyst such as concentrated sulfuric acid or concentrated hydrochloric acid at elevated temperatures. This esterification reaction will yield phenyl benzoate along with water as a byproduct. Purification techniques such as distillation can then be used to isolate the desired product.
How do you make phenyl benzoate from phenyl?
WE HAVE WHITE PHENYL SOLUTION FROM WHICH YOU CAN MAKE UPTO 50 LITERS OF WHITE PHENYLE. ONLY YOU HAVE TO ADD WATER TO THE SOLUTION SLOWLY.CONTACT US AT 9414033040, 9314813795 , aditya.rawat@gmail.comHINDAUN CITY, RAJASTHAN, INDIA
What is the electronegativity of phenyl salicylate?
Phenyl salicylate has a covalent electronegativity. This means that the chemical bonds in the substanceÊshare electrons among the different atoms.Ê
Is phenyl acetate or butyric acid more polar?
Phenyl acetate is less polar than butyric acid. This is because butyric acid has more polar functional groups present (carboxylic acid) compared to phenyl acetate (ester).
