Birmingham Al.
Pearl, Ms just to the East of Jackson would be your halfway exit with Hotels and Food.
The city that is roughly halfway between Shreveport, Louisiana, and Gadsden, Alabama, is likely Birmingham, Alabama. Birmingham is located in central Alabama and serves as a convenient midpoint for travelers between these two locations. It offers various amenities and attractions, making it a suitable stopover point.
Tanner, Alabama off US 65
Just east of Milledgeville, GA is halfway.
Jackson, MS......
Richmond, Virginia would be a good place to stop halfway while driving between Middletown and Covington.
Birmingham, Alabama is approximately 93 miles away from Montgomery, Alabama. The halfway point between Montgomery and Birmingham is Collins Chapel, Alabama.
The halfway point between Pearland, TX and Sulphur, Louisiana is Hamshire, TX.
Both New Mexico and Texas could be considered to be the approximate halfway point between Nevada and Louisiana. Take a look at the link below for a map showing the drive with directions from New Orleans, Louisiana to Reno, Nevada. Sites like meetways.com allow you to find a halfway point between 2 addresses.
The halfway point between Englewood, Florida and Covington Indiana falls in or around Canton Road, Marietta, Georgia.
Birmingham, Alabama is halfway between Knoxville & Jackson
Peavy, Alabama is halfway between Pensacola and Seiverville