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Yes.

*All* varieties of mushrooms should be cooked before eating them. Yes, this does include button mushrooms, the ones commonly found raw on salads.

According to Dr. Weil:

Mushrooms have very tough cell walls and are essentially indigestible if you don't cook them. Thoroughly heating them releases the nutrients they contain, including protein, B vitamins, and minerals, as well as a wide range of novel compounds not found in other foods...

But there are other reasons to cook your mushrooms. Raw mushrooms contain small amounts of toxins, including some compounds that are considered carcinogens. These are destroyed by cooking them thoroughly. Broiling or grilling is best.

And Dr. Fuhrman:

Avoid Uncooked Mushrooms

It's important to remember that mushrooms should only be eaten cooked. Several raw culinary mushrooms contain a potentially carcinogenic substance called agaritine, and cooking mushrooms significantly reduces their agaritine content.

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