Handicapped is the term used, if some part is missing. disease is substituted by illness.
prosthesis
prosthesis
prosthesis
The replacement of a missing bodily part with an artificial substitute is known as prosthetics. Prosthetics can help improve function and quality of life for individuals who have lost a limb or other body part due to injury, illness, or congenital conditions. Advances in technology have resulted in more advanced and customizable prosthetic devices to meet individual needs.
Candy is missing her left leg below the knee.
brain
In the series kyle xy the part that is missing is his belly button
what effect does Tay-sachs disease have on the body?
Tongue
Bones
intestine
Arms.