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Minamata disease is a neurological condition caused by severe Mercury poisoning. It was first identified in the 1950s in Minamata Bay, Japan, where industrial discharge of mercury contaminated local fish, leading to widespread consumption by the population. Symptoms include ataxia, numbness, and cognitive impairments, and in severe cases, it can result in death. The disease highlighted the dangers of environmental pollution and led to increased awareness and regulations regarding toxic substances.

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