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About 980 miles taking this route:

  1. Take I-10 EAST, from Houston, to I-75 SOUTH to TAMPA at EXIT 296A, in LAKE CITY, FLORIDA, via I-12 EAST to bypass New Orleans (EXIT 159 off I-10 in Baton Rouge to get onto I-12 EAST to HAMMOND ; EXIT 85C off I-12, near Slidell to continue on I-10 EAST towards BAY St. Louis).
  2. Take I-75 SOUTH to I-275 SOUTH to TAMPA at EXIT 274.
  3. Take I-275 SOUTH into Tampa.
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