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It was on May 14, 196, that Edward Jenner from Berkely, Gloucestershire, England first atempt to create a vaccine. He extracted the contents of a pustule fro the arm of a cowpox infected milkmaid, Sarah Nelmen, and injected it into the arm of eight-year-old James Phipps. As Jenner expected, immunization or vaccination with the cowpox virus caused only mild symptoms in the boy. When he subsequently inoculated the boy with smalllpox virus, the boy showed no symtomps of disease. The procedure is repeated to many paptients. By 1800 the practice is known as variolationhad began in America and by 1805 Napoleon Bonaparte had oredered all French solders to be vaccinated.

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