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What has the author Wesley D Leung written?
Wesley D. Leung has written: 'The role of apolipoprotein D in vascular smooth muscle cell migration'
What has the author Kathleen L Wyne written?
Kathleen L. Wyne has written: 'Regulation of apolipoprotein E synthesis in rat ovarian granulosa cells'
What has the author Changiz Taghibiglou written?
Changiz Taghibiglou has written: 'Molecular mechanisms regulating the assembly and secretion of apolipoprotein B in hamster liver and its overproduction in insulin resistant states'
What does the medical abbreviation APO mean?
APO can be short for apolipoprotein or, in the British spelling, acute pulmonary oedema. It can also mean as per ordered.APO = Take medication with food. NPO means no food.
What combines with cholesterol to form LDLs?
Low-Density Lipoproteins (LDLs) are formed when cholesterol combines with proteins, phospholipids, and triglycerides. Specifically, apolipoprotein B-100 (ApoB-100) is the primary protein component that facilitates the transport of cholesterol and triglycerides in the bloodstream. This combination allows LDLs to deliver cholesterol to cells throughout the body, playing a crucial role in lipid metabolism.
How frequent is the Apolipoprotein gene related to poor recovery from head injuries like concussions?
As you might be aware, it's rather difficult to attain enough brain tissue samples from surviving traumatic brain injury (TBI) patients in order to conduct a proper populations study. However, 30% of all TBI fatalities have been found to contain APP deposits. See link below.
Where is the milano gene located and how different isit from a normal gene?
The Milano gene is a variation of the gene that encodes for a protein called Apolipoprotein A-I. It is mainly found in individuals with a familial form of low HDL cholesterol levels. The difference lies in a single amino acid substitution in the protein sequence, resulting in functional changes and potential protective effects against cardiovascular disease.
How do you find out if you have apolipoprotein?
All people, and animals, have apolipoproteins. These are a family of proteins that perform many functions in your body. Most help carry fats throughout your bloodstream and are related to your cholesterol level. Some apolipoproteins have been linked to diseases, depending on the particular variant of protein. For example, apoE may be related to Alzheimer's dementia and apoA-I may be protective against heart disease. A doctor may be able to order a laboratory test to determine the variant of a certain protein you have. However, it may be expensive, unavailable or unnecessary.
What do lipase in the large intestines do?
The chylomicrons are capable of transporting dietary triacyglycerols from the intestine to peripheral tissues. The liloprotein lipases can hydrolyze triacylglycerols. The remnants are then taken up by the liver with the aid of the apolipoprotein apoE and these remants are degraded in the liver.The very low density lipoprotein tansports triacyglycerols from the liver to peripheral tissues instead. When it is hydrolyzed by lipoprotein lipase, it loses the triacyglycerols and gets transformed into low density lipoproteins.
Familial dysbetalipoproteinemia?
DefinitionFamilial dysbetalipoproteinemia is a disorder passed down through families in which there are high amounts of cholesterol and triglycerides in the blood.Alternative NamesType III hyperlipoproteinemia; Deficient or defective apolipoprotein ECauses, incidence, and risk factorsA genetic defect causes this condition. The defect results in the buildup of large lipoprotein particles that contain both cholesterol and triglycerides, a type of fat. The disease is linked to defects in the gene for apolipoprotein E in many cases.Hypothyroidism, obesity, or diabetes can make the condition worse. Risk factors for familial dysbetalipoproteinemia include a family history of the disorder or coronary artery disease.SymptomsSymptoms may not be seen until age 20 or older.Yellow deposits of fatty material in the skin called xanthomas may appear on the eyelids, palms of the hands, soles of the feet, or on the tendons of the knees and elbows.Atherosclerosisdevelops at an early age. There may be early chest pain (angina) or decreased blood flow to specific parts of the body, causing transient ischemic attacks of the brain or peripheral artery disease with claudication.Signs and testsTests that may be done to diagnose this condition include:AngiogramGenetic testing for apolipoprotein E (apoE)Heart stress testTotal cholesterolTriglyceride levelVery low density lipoprotein (VLDL) testTreatmentThe goal of treatment is to control underlying conditions such as obesity, hypothyroidism, and diabetes.Reducing calories, saturated fats, and cholesterol may significantly reduce cholesterol levels.See also: Heart disease and dietIf high cholesterol and triglyceride levels continue despite diet changes, your doctor may recommend medication to lower your triglyceride and cholesterol levels. Medicine to lower blood triglyceride and cholesterol levels include:Bile acid-sequestering resinsFibrates (gemfibrozil, fenofibrate)Nicotinic acidStatinsExpectations (prognosis)People with this condition have an increased risk for coronary artery disease and peripheral vasculardisease.With treatment, most people show a significant reduction in lipid levels.ComplicationsHeart attackStrokePeripheral vascular diseaseIntermittent claudicationGangrene of the lower extremitiesCalling your health care providerCall your health care provider if you have been diagnosed with this disorder and:New symptoms developSymptoms do not improve with treatmentSymptoms get worsePreventionScreening the family members of those with familial dysbetalipoproteinemia may lead to early detection and treatment.Early treatment and avoiding other risk factors for vascular disease (such as smoking) are crucial to preventing early heart attacks, strokes, and blocked blood vessels.ReferencesMahley RW, Weisgraber KH, Bersot TP. Disorders of lipid metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.Semenkovich CF. Disorders of lipid metabolism. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 217.
What are some words that have the root poli- in it?
5-letter wordspolio, polis6-letter wordspolice, policy, poling, polios, polish, polite, polity7-letter wordscipolin, policed, polices, politer, politic, tripoli8-letter wordscipolins, depolish, impolicy, impolite, policies, policing, polished, polisher, polishes, politely, politest, politick, politico, politics, polities, propolis, repolish, spoliate, tripolis, unpolite9-letter wordsacropolis, duopolies, impolitic, necropoli, nonpolice, policeman, policemen, polishers, polishing, politburo, politesse, political, politicks, politicos, scapolite, spoliated, spoliates, spoliator, unpoliced10-letter wordsantipolice, apolitical, cosmopolis, depolished, depolishes, hypolimnia, impolicies, impolitely, metropolis, monopolies, monopolise, monopolist, monopolize, necropolis, poliovirus, politburos, politeness, politesses, politician, politicise, politicize, politicked, politicker, politicoes, propolises, repolished, repolishes, scapolites, spoliating, spoliation, spoliators, trampoline, unpolished11-letter wordsacropolises, cosmopolite, depolishing, duopolistic, geopolitics, hypolimnion, impolitical, impoliticly, megalopolis, monopolised, monopolises, monopolists, monopolized, monopolizer, monopolizes, oligopolies, outpolitick, pitchpoling, policewoman, policewomen, politically, politicians, politicised, politicises, politicized, politicizes, politickers, politicking, realpolitik, repolishing, spoliations, superpolite, trampoliner, trampolines, unpolitical12-letter wordsantipolitics, apolitically, bibliopolist, cosmopolises, cosmopolitan, cosmopolites, depoliticize, despoliation, geopolitical, impoliteness, metropolises, metropolitan, monopolising, monopolistic, monopolizers, monopolizing, necropolises, nonpolitical, outpoliticks, policyholder, polioviruses, politenesses, politicalize, politicising, politicizing, realpolitiks, trampoliners, trampolining, trampolinist, valpolicella13-letter wordsantipolitical, bibliopolists, cosmopolitans, cosmopolitism, depoliticized, depoliticizes, despoliations, geopolitician, impolitically, megalopolises, megalopolitan, metropolitans, nonpolitician, oligopolistic, outpoliticked, policyholders, poliomyelitis, politicalized, politicalizes, semipolitical, trampolinings, trampolinists, valpolicellas14-letter wordsantimonopolist, apolipoprotein, cosmopolitisms, depoliticizing, geopolitically, geopoliticians, impolitenesses, megalopolitans, monopolization, nonpolitically, nonpoliticians, outpoliticking, politicalizing, politicization, sociopolitical15-letter wordsantimonopolists, apolipoproteins, cosmopolitanism, monopolizations, nonmetropolitan, poliomyelitides, politicizations16-letter wordscosmopolitanisms, depoliticization, monopolistically, nonmetropolitans, politicalization17-letter wordsdepoliticizations, politicalizations
What disease can you get from lack of Vitamin C?
Scurvy is the main one. It's not very common now, but it was a big problem back when sailors would be off at sea for months with no access to fresh fruits or vegetables. This is a reputable source with more information on scurvy: <http://dermnetnz.org/systemic/scurvy.html>
