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'coz it does... u got prob??': Yeah, I'm sure that wasn't a particularly enlightening answer...So, I'll have a stab at it below.

Muscle tissue, specifically, skeletal muscle, is used for energy during starvation. This is simply because muscle tissue contains a (relatively) great deal of non-essential structural protein, that can be used to provide energy without *immediately* causing death. Amino acids derived from hydrolyzed muscle protein can actually be used as sources of energy. Indeed, amino acids are classified as ketogenic and glucogenic, depending on if they can yield ketone bodies (acetoacetate, 3-hydroxybutarate) and acetyl-CoA or carbohydrate precursors (eg. oxaloacetate; pyruvate), respectively.

But what's the energy liberated from muscle tissue used for? Simply, to provide energy for organs more crucial than skeletal muscle, basically the brain. The amino acids from skeletal muscle can be converted to carbohydrate precursors which enter the gluconeogenic pathway, creating new glucose, which the brain can use for energy (brain-and nervous tissue-prefer glucose to all respiratory substrates). In addition, cells and organs without mitochondria, such as red blood cells, the kidney cotex and testes, better known as balls (yeah, that's right: its done for the family jewels too) can ONLY use glucose for energy, as only glucose can be anaerobically respired. In fact, some types of skeletal muscle fibres (type 1/white/fast twitch/glycolytic) too can only use glucose for energy as they have little to no mitochondria. The ketones derived from muscle protein are alternate sources of energy for the brain, kidneys (excluding their cotices, as aforementioned) and...skeletal muscle.

So that, in a nutshell, is why the body uses muscle tissue for energy.

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14y ago

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