Glomerular hydrostatic pressure is the pressure exerted by the blood in the glomerular capillaries of the kidney. It is a crucial force responsible for the filtration of blood in the renal corpuscle. An appropriate balance of this pressure helps maintain normal kidney function by ensuring effective filtration of waste and excess substances from the blood.
The Net Filtration Pressure (NFP) at the glomerulus is the difference between the net hydrostatic pressure and the blood colloid osmotic pressure acting across the glomerular capillaries. Under normal circumstances we can summarize this as NFP = NHP - BCOP or NFP = 35mm Hg - 25 mm Hg = 10mm Hg This is the average pressure forcing water and dissolved materials out of the glomerular capillaries and into the capsular spaces.
25
High blood pressure, or hypertension, can impair normal exchange at capillaries by causing increased hydrostatic pressure within the capillaries. This elevated pressure can lead to the disruption of the fluid balance, resulting in excess fluid leakage into surrounding tissues, potentially causing edema. Additionally, high pressure may damage the delicate capillary walls, reducing their permeability and hindering the effective exchange of oxygen, nutrients, and waste products between blood and tissues. Overall, these changes can compromise tissue health and function.
Pulmonary agents can cause pulmonary edema by disrupting the normal balance of fluid in the lungs, leading to fluid accumulation in the air sacs (alveoli) and interstitial spaces. This can result from mechanisms such as increased capillary permeability, inflammation, or increased hydrostatic pressure in the pulmonary circulation. Ultimately, this leads to impaired gas exchange and breathing difficulties.
is the force responsible for moving fluid across capillary walls. It is the difference between net hydrostatic pressure and net osmotic pressure. NFP= Net hydrostatic pressure - net osmotic pressure
70
Since there are no valves between the pulmonary capillaries and the left atrium, PCWP is a reflection of the LAP. During diastole, when mitral valve is open, the PCWP reflects LVEDP. LVEDP is an index of left ventricular end-diastolic volume. Here is a helpful URL to further clarify this entry. http://medind.nic.in/iad/t02/i4/iadt02i4p298.pdf
Glomerular filtration is a passive process in which hydrostatic pressure forces fluids and solutes through a membraneThe glomerular filtration rate (GFR) is directly proportional to the net filtration pressure and is about 125 ml/min (180 L/day).The glomeruli function as filters. High glomerular blood pressure (55 mm Hg) occurs because the glomeruli are fed and drained by arterioles, and the afferent arterioles are larger in diameter than the efferent arterioles.
I'm guessing that your issue is that force is a vector quantity? It turns out that hydrostatic force is always normal to the surface, so it can be treated as a scalar; only the magnitude is important.
HPg - Much like other capillaries in the body, hydrostatic pressure within the glomerular capillaries produces net outward movement of fluid. Unique to glomerular capillaries, HPg is consistently higher than other capillaries (~55 mm Hg), which ensures the one-way movement of fluid and solutes out of the glomerulus under normal conditions.
Net filtration would decrease. Source Mastering A and P book, chapter 25.