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Should I use clotrimazole cream or miconazole nitrate to treat athletes foot?
Wiki User
∙ 16y ago
It's surprisingly difficult to get information on this, considering how common athletes foot is. Clotrimazole and miconazole seem to be equally effective at treating athletes foot.2,3 Miconazole seems like it works quicker, but is also more concentration dependent1. Any differences are marginal, and I would use whichever is cheaper.
A better choice would be an allylamine like terbinafine (Lamisil). Topical allylamines have a relative effectiveness of 3.6 vs. placebo, whereas topical azoles only have a relative effectiveness of 2.1.2,3
1. EM Scott et al. Effect of miconazole and clotrimazole on K+ release and inhibition of ergosterol biosynthesis in Trichophyton mentagrophytes and related ultrastructural observations. Journal of Antimicrobial Chemotherapy (1986) 17, 423-432
2. R Hart et al. Systematic review of topical treatments for fungal infections of the skin and nails of the feet. BMJ 1999 319: 79-82.
3. SEM Bell-Sayer et al. A systematic review of oral treatments for fungal infections of the skin of the feet. Journal of Dermatological Treatments 2001 12: 69-74.
Wiki User
∙ 16y ago
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