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non protein nitrogen substances are urea, uric acid , ammonia, creatine

-The determination of nonproteinnitrogenous substances in the blood has traditionally been used to monitor renal function.

- The term nonprotein nitrogen (NPN) originated in the early days of clinical chemistry when analytical methodology required that protein be removed from the sample before analysis

out of all Urea is principal non protein contributor.

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What is the nonprotein calorie to nitrogen ratio of a patient receiving TPN consisting of the following parentral nutrition solution 500ml 30 dextrose 500ml 20lipid 500ml 8.5 amino acid?

Calorie to nitrogen ratio= Kcals per day/gram nitrogen per day To find out nitrogen gms= protein in gms/ 6.25 500 ml of 8.5 amino acid has 42.5gms protein that divided by 6.25= 6.8 gms The calories from dextrose and lipids have 1000 and 510 calories respectively Now divide 1510 non protein calories/ 6.8 =222 Hope this helps


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