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How do fugu produce tetrodotoxin?

Updated: 10/15/2022
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GaleEncyofMedicine

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13y ago

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Scientists have found that toxic fugu have unique exocrine glands for the secretion of tetrodotoxin. The fish appear to actively produce the toxin, rather than passively acquire it from the environment.

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Q: How do fugu produce tetrodotoxin?
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Related questions

Are blowfish poisonous to eat?

Fugu (Blowfish or Pufferfish) contains lethal amounts of the poison tetrodotoxin in the organs, especially the liver area and ovaries, and also the skin. The poison, a sodium channel blocker, paralyzes the muscles while the victim stays fully conscious, and eventually dies from asphyxiation. Currently, there is no known antidote, and the standard medical approach is to try to support the respiratory and circulatory system until the poison wears off. As of 2008, advances in fugu research and farming have allowed some farmers to mass produce non-toxic fugu. Researchers surmised that fugu's tetrodotoxin came from eating other animals that had the tetrodotoxin-laden bacteria, and developed immunity over time. Many farmers now are producing 'poison-free' fugu by keeping the fugu away from tetrodotoxin-laden bacteria. Usuki, a town in Ōita Prefecture, became famous for selling non-poisonous fugu. No one has been poisoned eating it yet. -From the Wikipedia entry for Fugu.


What type of venom does a toadfish have?

It's a type of tetrodotoxin, a neurotoxic venom similar to the kind found in fugu (Japanese blowfish).


What health risks does the fugu pose?

The fugu and related species may contain a tetrodotoxin, an extremely potent neurotoxin and one of the most toxic substances known, which produces critical illness and often death.


Where is the poison located on a fugu fish?

Recent evidence has shown that tetrodotoxin (the poison present with fugu) is produced by certain bacteria and that these are the source of the toxin in pufferfish like fugu. It is speculated that the fugu picked up the bacteria by consuming other animals were contaminated with the bacteria - which doesn't hurt them because they have developed an immunity to the toxin. Some aquaculture farmers manage to produce "toxin free" fugu by keeping them away from the bacteria. The poison seems to accumulate in the organs (such as the liver and ovaries) and skin of the fugu. If improperly prepared, the toxin can spread to other parts of the fish.


What is the poison in a blowfish?

The poison in a blowfish is called, "tetrodotoxin" and can be lethal. Strict regulation for the preparation of blowfish (or Fugu) exists in many countries. Preparation has, on occasion, actually led to death.


What Japanese delicacy can be deadly if not prepared correctly?

Fugu, which Japanese for Puffer Fish, can be quite deadly if any of the tetrodotoxin in the organs contaminates the meat during cleaning of the fish and/or during preparation of the meal.


What is the structure of the bonds in tetrodotoxin?

See the wikipedia article on tetrodotoxin, TTX.


Is fugu poisonous?

Yes, fugu is poisonous, but if prepared properly then it is safe to eat.


Can you taste tetrodotoxin?

no


What is known as fugu to the Japanese?

"Fugu" is the Japanese word for "blowfish". PCH: Pufferfish


What is fugu poisoning?

when a person eats the flesh of a fugu, also known as a puffer fish, which contains lethal toxins.


What do fugu eat?

The fugu fish is an extremely poisonous fish found in the waters off Japan. Fugu fish, also called puffer fish, eat other fish, small crustaceans, and plankton.