Acetylcholinesterase is crucial for neurotransmission, as it breaks down the neurotransmitter acetylcholine in the synaptic cleft, terminating the signal between neurons and muscle cells. This enzyme prevents prolonged stimulation of muscles and ensures proper muscle function and coordination. Additionally, its activity is vital in the central nervous system for regulating synaptic transmission and maintaining cognitive functions. Dysregulation of acetylcholinesterase is associated with various neurological disorders, highlighting its importance in both normal physiology and disease.
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"Acetylcholinesterase" production results in the production of a glucosteroid inhibitor.
Acetylcholinesterase is pronounced uh-SEET-uhl-KOH-lin-ES-ter-ays.
neostigmine
Acetylcholine is degraded by acetylcholinesterase
ACHe
Nerve agents are compounds that have the capacity to inactivate the enzyme acetylcholinesterase (AChE)
Acetylcholinesterase is dangerous to humans as it attacks nerves and causes a loss of use in the affected area. Poisons and venoms contain these properties.
John A. Montgomery has written: 'Standard operating procedures for the determination of acetylcholinesterase activity' -- subject(s): Pesticides, Acetylcholinesterase, Toxicology
Acetylcholinesterase
acetylcholinesterase
Chemical
There are 3 different types of acetylcholinesterase inhibitors - short-acting, medium-duration and irreversible inhibitors, which differ in their interactions with the active site of acetylcholinesterase.=Neostigmine is a medium-duration acetylcholinesterase inhibitor that enhances cholinergic transmission in the central nervous system, autonomic nervous system and at neuromuscular junctions. Acetlycholinesterase inhibitors are an established therapy for Alzheimer's disease and dementia .=