"Usted es muy bienvenido" is the literal translation, but the meaning is a little different than what you would get in English. "Bienvenido" is a term used when greeting someone, expessing pleasure at their presence. "Bienvenido a mi casa" is "welcome to my house".
If you are replying to a act of thanks, you would more likely say "de nada".
To say "welcome to Venezuela" in Spanish, you would say "bienvenido a Venezuela."
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The phrase "Welcome to the States" translated into Spanish is "Bienvenidos a los Estados"
The correct way would be to say "you are very welcome."
Señor, le doy la más cordial bienvenida.
You're welcome handsome in Spanish is three simple words. To say "You're welcome handsome" in the Spanish language would simply be "de nada guapo" and can be easily said.
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"You are welcome" as in a greeting is "Bienvenida" (to a man you say "Bienvenido")"You are welcome" as in a response to "Thank you" is "De nada"