The "case for abstinence" refers to arguments and appeals to reason supporting the idea of abstaining (not doing) from an activity considered potentially dangerous or unhealthy, like having premarital sex, or doing drugs or alcohol.
A "case for abstinence" may also involve more subjective arguments involving religion and values, or even coercion and misinformation.
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Some but not all reasons for being abstinent include eliminating the chance or pregnancy and eliminating the chance of contracting and STD.