Answer
For this question there are two possible answers, Mathematics and Medicine.
Medicine is the hardest degree to apply to as higher grades are needed to enter the course, whereas the hardest degree to obtain is Mathematics very closely followed by Physics and then Engineering.
Physics and Engineering are difficult due in most part to their taxing applications of Mathematics onto real world problem solving. For those who aren't skilled in Applied Mathematics, yet succeed in Abstract Mathematics, these subjects may however seem more difficult than the broader topics of Pure Mathematics.
*edit*
I would disagree medicine would even make it into the top 10 hardest or most academically challenging degrees. I read medicine for 2 years at Edinburgh before opting for a career change, not because the course was taxing but because it was dull. I have since completed a BEng in Marine Technology and a MEng in composites engineering and I would say that both of them were not only more academically demanding but also require more common sense, problem solving and ability to work with complex equations, quickly and accurately. Medicine requires a vast amount of reading and research but is not taxing academically per say.
I agree that there are branches of mathematics which would make mere mortals heads collapse trying to understand.
I would suggest that Mathematics, Physics and Engineering are the most academically taxing degrees.
I would have to disagree with some of the other answers. People generally associate complex-sounding degrees, such as Medicine, Physics, and other science-based studies with hard work. But I'm am an English major: how would those B.S. degree holders feel about churning out monstrously long papers while keeping up with constant reading? An English degree requires not only that you hold knowledge in your brain, but that you have the creativity and natural ability to write. There is a massive workload involved with an English education.
The hardest college to get into in Colorado is Colorado School of Mining
hardest
Oxford.
Warner
hardest, harder
they both are about the same.
Chemical Engineering. It encompasses all the requirements of a Chemistry degree (Second hardest) and an Engineering degree. Be prepared to sit next to pre-medical students learning about chemistry. Be prepared to take the same courses as a Physics Major, same courses as a Math Major, and learn about thermodynamics that an Engineering Major will take.
University of Texas hands down Rice University is the hardest
Northwestern University is considered by many to be the hardest Big Ten university to get into.
The hardest conference in college baseball is a debatable topic. However, some argue that the Pac-12 conference is one f the most competitive.
A bachelor's degree is a college degree from which many specific programs of study fall.
A college degree is not required for this field.