If the light is flashing there is no resetting it. One or more of the pressure sensors has failed. Replace the faulty sensor, set the correct tire pressure on all 4 tires. Take it for a short drive and the light will reset itself. If the sensors are 4-5 years old the batteries are probably dead or going to die soon. Replace all the sensors and be done with it.
To reset the tire pressure monitoring system (TPMS) on a Lexus LS, first ensure that all tires are inflated to the recommended pressure. Then, turn the ignition to the "ON" position without starting the engine. Locate the TPMS reset button, usually found beneath the steering wheel, and press it until the TPMS light blinks three times. Finally, start the engine and drive for a few minutes to complete the reset process.
The 2009 Lexus GS-450H has 24 valves.
The 2013 Lexus RX-450H has 24 valves.
The 2014 Lexus GS-450H has 24 valves.
The 2012 Lexus RX-450H has a V6 engine.
The 2014 Lexus RX-450H has 24 valves.
The 2010 Lexus GS-450H has a V6 engine.
The 2013 Lexus GS-450H has a V6 engine.
The 2010 Lexus RX-450H has a V6 engine.
The 2011 Lexus RX-450H has a V6 engine.
The 2008 Lexus GS-450H has a V6 engine.
The 2014 Lexus GS-450H has a V6 engine.