Signal transduction refers to the process by which cells respond to external signals through a series of molecular events, often leading to changes in gene expression and cellular behavior. In carcinogenesis, dysregulation of these signaling pathways can lead to uncontrolled cell proliferation, evasion of apoptosis, and enhanced survival, contributing to tumor development and progression. Mutations in key signaling molecules or receptors can drive oncogenic processes, making understanding these pathways crucial for developing targeted cancer therapies. Thus, aberrant signal transduction plays a pivotal role in the initiation and advancement of cancer.
Signal transduction plays a crucial role in the regulation of haemopoiesis by facilitating communication between extracellular signals and the intracellular machinery of hematopoietic stem and progenitor cells. Growth factors and cytokines bind to specific receptors on these cells, initiating signaling cascades that influence cell proliferation, differentiation, and apoptosis. This process ensures the balanced production of various blood cell lineages in response to physiological needs, such as during stress or injury. Disruptions in signal transduction pathways can lead to hematological disorders, highlighting their importance in maintaining healthy haemopoiesis.
An ADPLL is an all-digital phase locked loop - a control system that generates an output signal whose phase is related to the phase of an input signal.
Convolution is particularly useful in signal analysis. See related link.
The most common methods concerning cable fault location revolve around the use of Time Domain Reflectometers (see related link) which in summary work by sending a signal down the cable line and then examining the 'reflection' of that signal. A mathematical algorithm then is used to compare the original signal to the reflected signal to determine the location of the fault. For those looking for a highly technical, academic paper on the subject, you can also view the related link.
The bandwidth of a signal is related to how fast you can transmit information over that signal. Signals with large (or broad) bandwidth can transmit more information (data) in a given amount of time, so this results in faster download times.
the role of Motif in signal transduction
Jannette Dorrestijn has written: 'Signal transduction related to the metabolic action of insulin' -- subject(s): Physiological effect, Glucose, Metabolism, Cellular signal transduction, Insulin
Which enzyme is responsible for phosphorylating target proteins in signal transduction pathways? Which second messenger is produced from the cleavage of phosphatidylinositol 4,5-bisphosphate in signal transduction? Which cell surface receptor is involved in the activation of the MAPK signaling pathway? What is the role of G proteins in signal transduction cascades?
A signal transduction is a really complicated process when a molecule signals to a receptor which then alters other molecules as a response to this. The signal can produce a wide variety of responses.
Protein phosphates turn off signal transduction pathways by removing the phosphate groups from the protein kinase, making them reusable and making the kinase inscribe stopping the signal transduction pathway.
Gary B. Willars has written: 'Receptor signal transduction protocols' -- subject(s): Methodology, Cell receptors, Cellular signal transduction, Signal Transduction, Laboratory Manuals, Physiology, Research
The act of conveying over.
John T. Hancock has written: 'Cell signalling' -- subject(s): Signal Transduction, Cell interaction, Physiology, Cellular signal transduction
Sudhir K. Sopory has written: 'Signal transduction in plants' -- subject(s): Plant cellular signal transduction, Plant molecular biology
Andrea Becchetti has written: 'Integrins and ion channels' -- subject(s): Integrins, Cellular signal transduction, Ion channels, Signal Transduction, Physiology, Ion Channels, Metabolism
signal reception signal transduction cellular response
Maurice B. Hallett has written: 'The Neutrophil' 'The molecular and ionic signalling of neutrophils' -- subject(s): Neutrophils, Lymphocyte transformation, Signal Transduction, Cellular signal transduction, Physiology