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Some disadvantages of genetically modified organisms are:

1- Genetic modifications results in formation of transgenic plants and animals. So there may be a chance of loss of genetic diversity upon wide use of this process on particular species, if care is not taken to preserve genetic material of the original organisms.

2- Artificial genetic modifications of a desired organism may result in simultaneous Natural Genetic (or other) modifications of a undesired organism. For example, on modifying a plant to be resistant to a particular disease causing organism, the latter may acquire natural variations which may enable it to infect other plant species not previously infected.

3- Some people complain that by modifying different agricultural plants to increase quantity, resistance etc. the natural taste and nutritional value of the food product may somehow get disrupted. However, this has not been scientifically proven.

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