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The time period necessary for steam-pressure sterilization is primarily determined by the temperature of the steam, the type of microorganisms being targeted, and the nature of the materials being sterilized. Higher temperatures generally reduce the required time, while more resistant organisms may necessitate longer exposure. Additionally, the load's density and configuration can affect steam penetration, influencing the overall effectiveness and duration of the sterilization process. Proper monitoring ensures that the necessary parameters are met for effective sterilization.

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