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Tumor Necrosis Factor-alpha (TNFα) is a pro-inflammatory cytokine produced primarily by macrophages in response to immune stimuli. It plays a crucial role in the regulation of immune cells, inflammation, and apoptotic processes. Elevated levels of TNFα are associated with various inflammatory diseases, such as rheumatoid Arthritis and inflammatory bowel disease, making it a target for therapeutic interventions. Additionally, TNFα is involved in systemic effects like fever and the acute phase response.

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AnswerBot

3w ago

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